TAP Family: NAC
Olsen et al (2005): NAC proteins constitute one of the largest families of plant-specific transcription factors, and the family is present in a wide range of land plants. Here, we summarize the biological and molecular functions of the NAC family, paying particular attention to the intricate regulation of NAC protein level and localization, and to the first indications of NAC participation in transcription factor networks. The recent determination of the DNA and protein binding NAC domain structure offers insight into the molecular functions of the protein family. Research into NAC transcription factors has demonstrated the importance of this protein family in the biology of plants and the need for further studies.
This TAP family belongs to the GCM domain factors structural class of the Beta-hairpin exposed by an alpha/beta-scaffold structural superclass, as defined in Plant-TFClass (Blanc-Mathieu et al. 2024)
References:
Olsen, AN; Ernst, HA; Leggio, LL; Skriver, K. 2005. NAC transcription factors: structurally distinct, functionally diverse. Trends Plant Sci. 10(2):79-87
Blanc-Mathieu, Romain et al. 2024. Plant-TFClass: a structural classification for plant transcription factors. Trends in Plant Science, Volume 29, Issue 1, 40 - 51
