TAP Family: GARP_ARR-B

Tajima et al (2004): In Arabidopsis thaliana, a Histidine-to-Aspartate (His-->Asp) phosphorelay is involved in the signal transduction for propagation of certain stimuli, such as plant hormones. Through the phosphorelay, the type-B phospho-accepting response regulator (ARR) family members serve as DNA-binding transcriptional regulators, whose activities are most likely regulated by phosphorylation/dephosphorylation.

This TAP family belongs to the Tryptophan cluster factors structural class of the Helix-turn-helix domains structural superclass, as defined in Plant-TFClass (Blanc-Mathieu et al. 2024)

References:

Aoyama, T; Oka, A. 2003. Cytokinin signal transduction in plant cells. J. Plant Res. 116(3):221-31

D'Agostino, IB; Kieber, JJ. 1999. Phosphorelay signal transduction: the emerging family of plant response regulators. Trends Biochem. Sci. 24(11):452-6"

Kakimoto, T. 2003. Perception and signal transduction of cytokinins. Annu Rev Plant Biol 54:605-27"

Tajima, Y; Imamura, A; Kiba, T; Amano, Y; Yamashino, T; Mizuno, T. 2004. Comparative studies on the type-B response regulators revealing their distinctive properties in the His-to-Asp phosphorelay signal transduction of Arabidopsis thaliana. Plant Cell Physiol. 45(1):28-39"

Blanc-Mathieu, Romain et al. 2024. Plant-TFClass: a structural classification for plant transcription factors. Trends in Plant Science, Volume 29, Issue 1, 40 - 51