TAP Family: CAMTA
Bouché et al (2002): Screening of cDNA expression libraries derived from plants exposed to stress, with 35S-labeled recombinant calmodulin as a probe, revealed a new family of proteins containing a transcription activation domain and two types of DNA-binding domains designated the CG-1 domain and the transcription factor immunoglobulin domain, ankyrin repeats, and a varying number of IQ calmodulin-binding motifs. Based on domain organization and amino acid sequence comparisons, similar proteins, with the same domain organization, were identified in the genomes of other multicellular organisms including human, Drosophila, and Caenorhabditis, whereas none were found in the complete genomes of single cell eukaryotes and prokaryotes. This family of proteins was designated calmodulin-binding transcription activators (CAMTAs).
This TAP family belongs to the GCM domain factors structural class of the Beta-hairpin exposed by an alpha/beta-scaffold structural superclass, as defined in Plant-TFClass (Blanc-Mathieu et al. 2024)
References:
Bouché, N; Scharlat, A; Snedden, W; Bouchez, D; Fromm, H. 2002. A novel family of calmodulin-binding transcription activators in multicellular organisms. J. Biol. Chem. 277(24):21851-61
Blanc-Mathieu, Romain et al. 2024. Plant-TFClass: a structural classification for plant transcription factors. Trends in Plant Science, Volume 29, Issue 1, 40 - 51
