TAP Family: ARID
Kortschak et al (2000): Members of the recently discovered ARID (AT-rich interaction domain) family of DNA-binding proteins are found in fungi and invertebrate and vertebrate metazoans. ARID-encoding genes are involved in a variety of biological processes including embryonic development, cell lineage gene regulation and cell cycle control. Although the specific roles of this domain and of ARID-containing proteins in transcriptional regulation are yet to be elucidated, they include both positive and negative transcriptional regulation and a likely involvement in the modification of chromatin structure.
References:
Kortschak, RD; Tucker, PW; Saint, R. 2000. ARID proteins come in from the desert. Trends Biochem. Sci. 25(6):294-9
Patsialou, A; Wilsker, D; Moran, E. 2005. DNA-binding properties of ARID family proteins. Nucleic Acids Res. 33(1):66-80"
Wilsker, D; Patsialou, A; Dallas, PB; Moran, E. 2002. ARID proteins: a diverse family of DNA binding proteins implicated in the control of cell growth, differentiation, and development. Cell Growth Differ. 13(3):95-106"
Wilsker, D; Probst, L; Wain, HM; Maltais, L; Tucker, PW; Moran, E. 2005. Nomenclature of the ARID family of DNA-binding proteins. Genomics 86(2):242-51"
Kortschak, RD; Tucker, PW; Saint, R. 2000. ARID proteins come in from the desert. Trends Biochem. Sci. 25(6):294-9"
Patsialou, A; Wilsker, D; Moran, E. 2005. DNA-binding properties of ARID family proteins. Nucleic Acids Res. 33(1):66-80"
Wilsker, D; Patsialou, A; Dallas, PB; Moran, E. 2002. ARID proteins: a diverse family of DNA binding proteins implicated in the control of cell growth, differentiation, and development. Cell Growth Differ. 13(3):95-106"
Wilsker, D; Probst, L; Wain, HM; Maltais, L; Tucker, PW; Moran, E. 2005. Nomenclature of the ARID family of DNA-binding proteins. Genomics 86(2):242-51"
