TAP Subfamily: CRF
(Rashotte & Goertzen, 2010) specify Cytokinin Response Factors (CRFs) as a subset of the AP2/ERF TF family. These proteins can be characterized by a N-terminal CRF domain relative to the AP2 DNA binding domain and by a CRF specific C-terminal region (Powell et al., 2019; Rashotte & Goertzen, 2010). CRF TFs are included in the cytokinin signal transduction pathway in the course of leaf development (Rashotte & Goertzen, 2010). (Rashotte & Goertzen, 2010) performed database searches, motif, and phylogenetic analyses to identify CRF genes in representatives of all major land plant lineages.
References:
Rashotte, A. M., & Goertzen, L. R. (2010). The CRF domain defines Cytokinin Response Factor proteins in plants. BMC Plant Biology, 10(1), 74. https://doi.org/10.1186/1471-2229-10-74
Powell, R. V., Willett, C. R., Goertzen, L. R., & Rashotte, A. M. (2019). Lineage specific conservation of cis-regulatory elements in Cytokinin Response Factors. Scientific Reports, 9(1), 13387. https://doi.org/10.1038/s41598-019-49741-6
